Selected publications
Piratsu N*, Cordioli M*, Nandakumar P, Mignogna G, […], Nivard MG*, Perry J*, Ganna A*. Genetic analyses identify widespread sex-differential participation bias. Nature Genetics. 2021
The COVID-19 Host Genetics Initiative, Neale BM*, Daly MJ*, Ganna A* Mapping the human genetic architecture of COVID-19. Nature. 2021
The COVID-19 Host Genetics Initiative, Neale BM*, Daly MJ*, Ganna A* A first update on mapping the human genetic architecture of COVID-19. Nature. 2022
The COVID-19 Host Genetics Initiative, Neale BM*, Daly MJ*, Ganna A* A second update on mapping the human genetic architecture of COVID-19. Nature. 2023
Jukarainen S, Kiiskinen T, Havulinna SA, Karjalainen J, Cordioli M, […], Ganna A. Genetic risk factors have a substantial impact on healthy life years. Nature Medicine. 2022
Hartonen T*, Jermy B*, Sõnajalg H, Vartiainen P, Krebs K, Vabalas A, FinnGen, Estonian Biobank Research Team, Leino T, Nohynek H, Sivelä J, Mägi R, Daly MJ, Ollila HM, Milani L, Perola M, Ripatti S, Ganna A. Nationwide health, socio-economic and genetic predictors of COVID-19 vaccination status in Finland. Nature Human Behaviour. 2023
Mignogna G, Carey EC, Wedow R, Baya N, Cordioli M, Piratsu N, Bellocco R, Nivard MG, Neale BM, Walters KR*, Ganna A*. Patterns of item nonresponse behavior to survey questionnaires are systematic and have a genetic basis. Nature Human Behaviour. 2023.
Lee J, Jukarainen S, Dixon P, Davies NM, Davey Smith, G, Natarajan P, Ganna A. Quantifying the causal impact of biological risk factors on healthcare costs. Nature Communications. 2023
Vartiainen P, Jukarainen S, Rhedin SA, Prinz A, Hartonen T, Vabalas A, Viippola E, Rodosthenous RS, Kuitunen S, Liu A, Lundholm C, Smew AI, Osvald EC, Helle E, Perola M, Almqvist C, Heinonen S*, Ganna A*. Risk factors for severe respiratory syncytial virus infection during the first year of life: development and validation of a clinical prediction model. Lancet Digital Health. 2023
Wharrie S, Yang Z, Ganna A, Kaski S Characterizing personalized effects of family information on disease risk using graph representation learning. Proceedings of the 8th Machine Learning for Healthcare Conference, PMLR, 2023
Liu A*, Genovese G*, Zhao Y*, […], FinnGen, BCAC, MVP, Loh P*, Ganna A*, Perry, JRB*, Machiela MJ*. Population analyses of mosaic X chromosome loss identify genetic drivers and widespread signatures of cellular selection. Nature, 2024
Jermy B*, Läll K, Wolford B*, Wang Y, […] Mars N, Ganna A*, Ripatti S*. A unified framework for estimating country-specific cumulative incidence for 18 diseases stratified by polygenic risk. Nature Communicaton, 2024
Vabalas A, Hartonen T, Vartiainen P, Jukarainen S, Viippola E, Rodosthenous RS, Liu A, Hägg S, Perola M, Ganna A. Deep learning-based prediction of one-year mortality in Finland is an accurate but unfair aging marker. Nature Aging, 2024
Cordioli M*, Corbetta A*, Kariis HM*, Jukarainen S, Vartiainen P, Kiiskinen T, Ferro M, FinnGen, Estonian Biobank research team, Perola M, Lehto K, Niemi M, Ripatti S, Milani L, Ganna A. Socio-demographic and genetic risk factors for drug adherence and persistence across 5 common medication classes. Nature Communications, 2024
Current preprints
Detrois K*, Tuomo H*, Teder-Laving M, Jermy B, Läll K, Yang Z, Estonian Biobank research team, FinnGen, Mägi R, Ripatti S, Ganna A. Transferability and accuracy of electronic health record-based predictors compared to polygenic scores. medRxiv 2024
German J*, Cordioli M*, Tozzo V, […] Loos R.J.F, Vainik U, Ganna A. Association between plausible genetic factors and weight loss from GLP1-RA and bariatric surgery: a multi-ancestry study in 10 960 individuals from 9 biobanks medRxiv, 2024
Wang F*, Liu A*, Yang Z, […], Perola M, Tuomi T*, Ganna A*. Effect of parental autoimmune diseases on type 1 diabetes in offspring can be partially explained by HLA and non-HLA polymorphisms: a nationwide registry and biobank-based study in 7.2M Finns. medRxiv, 2024
Yang Z, Pajuste F, Zguro K, […] Ripatti S, Mars N, Ganna A. Limited overlap between genetic effects on disease susceptibility and disease survival. medRxiv, 2023